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October 17, 1975Science

Human Interferon Production: Superinduction by 5,6-Dichloro-1-β-D-Ribofuranosylbenzimidazole

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PSPravinkumar B. SehgalNational Institute of High Security Animal DiseasesITIgor TammRockefeller FoundationJVJ VilčekNew York University

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Sehgal et al. (1975) studied this question.

synapsesocial.com/papers/6a91207a17bbbfe73e745dd2https://doi.org/10.1126/science.1179208
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Also Consider

Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Nucleolar necklaces in chick embryo fibroblast cells. I. Formation of necklaces by dichlororibobenzimidazole and other adenosine analogues that decrease RNA synthesis and degrade preribosomes.1975 · 67 citations
  2. 2Stabilization of Interferon Messenger RNA Activity by Treatment of Cells with Metabolic Inhibitors and Lowering of the Incubation Temperature1973 · 120 citations