This case report describes a rare instance of breast angiosarcoma treated with modified radical mastectomy and adjuvant IL-2, with no recurrence at 10 months.
May support adjuvant IL-2 post-mastectomy in rare breast angiosarcoma; hypothesis-generating and should not change practice.
A case of angiosarcoma of the brest which is a very rare entity with poor prognosis is presented in this paper. A 24-year-old female was admitted to the hospital because of a rapidly enlarging tumor of the right breast. A 10×10cm elastic soft and illdefined tumor was palpated in the right breast. The skin over the tumor was bluish in color. Histological study of open biopsied specimen revealed angiosarcoma. Modified radical mastectomy was performed. In this particular case, 700, 000 unit IL-2 was intravenously administered for 14 days as postoperative adjuvant chemotherapy. She is leading a normal social life 10 months after the surgery without any recurrent signs. A case of angiosarcoma of the brest is very rare and only 18 cases including our case have been reported in the Japanese literature. A careful follow-up study is necessary, because the prognosis of this entity is extremery poor, although histological findings only show a mild atypism.
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Tachibana et al. (1996) studied this question.
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