Why the study?
Do eNOS gene polymorphisms influence susceptibility to cerebral malaria in Indian adults?
Do eNOS gene polymorphisms influence susceptibility to cerebral malaria in Indian adults?
The eNOS Glu(298)-->Asp polymorphism and 'C-b-Asp' haplotype are associated with protection against cerebral malaria in Indian adults, potentially via enhanced NO production.
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Should not alter malaria risk assessment or prevention; hypothesis-generating in Indian adults and requires prospective validation.
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Dhangadamajhi et al. (2009) studied this question.
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