A theoretical study of the expected distribution of Escherichia coli serotypes among samples randomly drawn from populations containing different numbers, ranging from 2 to 40, was compared with experimental data based on the examination of 10 and 100 coiony samples from the same specimens. From these studies it was possible to lay down guide lines for the planning of efficient sampling programmes for determining most or all serotypes present in various animal species.
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Hedges et al. (1977) studied this question.
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