Why the study?
Does an increase in middle cerebral artery flow velocity during the initial phase of cardiopulmonary bypass predict neurological dysfunction in patients undergoing CABG?
Does an increase in middle cerebral artery flow velocity during the initial phase of cardiopulmonary bypass predict neurological dysfunction in patients undergoing CABG?
Overperfusion of the basal cerebral arteries during the initial phase of cardiopulmonary bypass may contribute to post-operative neurological dysfunction.
Marked MCA velocity increases were associated with neurological complications after CABG; hypothesis-generating and requires prospective validation before guiding practice.
One hundred twenty-seven patients undergoing coronary artery bypass graft surgery were monitored by transcranial Doppler ultrasonography. Five patients had more than 50% increases in middle cerebral artery mean flow velocity during the initial phase (10-120 sec) of cardiopulmonary bypass. Four of these 5 developed neurological complications including stroke and encephalopathy. These results indicate that overperfusion of the basal cerebral arteries during cardiopulmonary bypass procedures may contribute to neurological dysfunction after the surgery.
No takes yet. Share an insight, caveat, or question.
Brillman et al. (1995) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: