Why the study?
How does cardiopulmonary bypass affect cerebral blood flow in patients undergoing elective coronary revascularisation?
Population
51 patients undergoing elective coronary revascularisation using a standardised anaesthetic and surgical…
Comparison
Cardiopulmonary bypass (CPB) vs Pre-bypass baseline
Design
Cohort
Follow-up
Immediately following cardiopulmonary bypass
Authors
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May raise cerebral dysfunction risk on bypass in CABG; leaves open whether PaCO2 targets alter outcomes in trials.
How does cardiopulmonary bypass affect cerebral blood flow in patients undergoing elective coronary revascularisation?
Cerebral blood flow decreases during cardiopulmonary bypass and correlates with PaCO2, suggesting that maintaining normocarbia may minimize the risk of low cerebral blood flow and subsequent cerebral dysfunction.
Venn et al. (1988) studied this question.
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