Answers are grounded in this paper and cite their sources.
1 The activity of RNA polymerase solubilized from rat liver nuclei is higher with denatured than with native DNA. 2 The synthesis of RNA is stimulated, and proceeds for a longer time, upon addition of ammonium sulphate with denatured DNA, and of spermine with native DNA. 3 The effects of ammonium sulphate and of spermine occur in the presence of Mn2+ but not of Mg2+.
No takes yet. Share an insight, caveat, or question.
Stirpe et al. (1970) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: