A tailor-made, two-component molecular system bound to a GaAs-based electronic device has been used to detect nitric oxide (NO) in physiological buffer solutions down to a concentration of 1 ppm (ca. 3 μM). This is made possible because the current through the GaAs changes when NO binds to an iron(III) porphyrin (see picture).
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Wu et al. (2000) studied this question.
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