Ambulatory blood pressure of adults in Novosibirsk, Russia: interim report on a population study

Objective To describe the distributions of the ambulatory blood pressure in a sample drawn from the Siberian population. Methods In the European Project On Genes in Hypertension (EPOGH), a random population sample of 162 persons (72 men and 90 women) was investigated in Novosibirsk, Russia. Mean age (± SD) was 40.6 ± 15.3 years. Validated oscillometric 90207 SpaceLabs monitors were programmed to obtain ambulatory blood pressure readings at intervals of 15 min from 0800 h to 2200 h and at 30 min intervals from 2200 h to 0800 h. Daytime and nighttime were defined using short fixed-clock time intervals, which ranged from 1000 h to 2000 h and from midnight to 0600 h, respectively. Results In the 162 participants, of whom 54 were hypertensive, 24-h clocktime day and clocktime night blood pressures averaged 120/73, 126/79 and 110/60 mmHg, respectively. Compared with daytime values, blood pressures at the clinic were 5.7/1.1 mmHg lower in 108 normotensive people, but 17.0/13.1 mmHg higher in 54 hypertensive patients. In the normotensive subgroup, the 95th percentiles of the 24-h clocktime day and clocktime night blood pressures were 128/81, 136/86 and 118/72 mmHg, respectively. Conclusion In comparison with other population surveys, the present interim report on the EPOGH study produced consistent results with respect to the distributions of the ambulatory measurements both in normotensive subjects and in the overall study population.