What question did this study set out to answer?

To establish a rapid, simple purification procedure for isolating biologically active S antigen from retinal tissue.

December 4, 2009Ophthalmic Research

A Simple and Rapid Method for Isolation of Retinal S Antigen

View Full Paper

Ask AI

Bookmark

Authors

CDChristiane DoreyCentre de Recherche des Cordeliers JCJ. CozetteCentre de Recherche des Cordeliers JFJean‐Pierre FaureUniversité de Poitiers

Discussion

Member takes

Implication

Experimental protocol demonstrates rapid purification of retinal S antigen from retinal tissue, highlighting preserved antigenicity for inducing uveoretinitis.

Key Points

To establish a rapid, simple purification procedure for isolating biologically active S antigen from retinal tissue.
Retinal tissue was processed sequentially using salt precipitation and gel filtration.
Final purification was conducted via adsorption chromatography on hydroxyapatite-agarose.
The isolation protocol yielded highly purified retinal S antigen.
Purified S antigen retained high antigenicity and pathogenic activity, successfully inducing experimental autoimmune uveoretinitis.

Cite This Study

Dorey et al. (2009) studied this question.

synapsesocial.com/papers/6a913e12be68d22e6965e778 https://doi.org/10.1159/000265199

View Full Paper

Ask AI

Bookmark

Implication

Experimental protocol demonstrates rapid purification of retinal S antigen from retinal tissue, highlighting preserved antigenicity for inducing uveoretinitis.

A Simple and Rapid Method for Isolation of Retinal S Antigen

Discussion

Member takes

Implication

Key Points

Cite This Study

A Simple and Rapid Method for Isolation of Retinal S Antigen

Discussion

Member takes

Implication

Key Points

Cite This Study

Also Consider

Also Consider