Why the study?
Does rosuvastatin 20 mg reduce the occurrence of new ischemic lesions on DWI in statin-naïve acute stroke patients?
Population
316 statin-naïve acute stroke patients who underwent diffusion-weighted imaging within 48 hours after…
Comparison
Rosuvastatin 20 mg vs Placebo
Design
RCT, randomized, double-blind
Follow-up
14 days
Authors
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Does not support rosuvastatin to reduce new DWI lesions in statin-naïve acute stroke; leaves open effects on hemorrhagic transformation.
Does rosuvastatin 20 mg reduce the occurrence of new ischemic lesions on DWI in statin-naïve acute stroke patients?
In statin-naïve acute stroke patients, rosuvastatin 20 mg did not significantly reduce new ischemic lesions on DWI but was safe and associated with a lower rate of hemorrhagic transformation.
Heo et al. (2016) studied this question.
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