This case report highlights the rare possibility of fibrosarcoma developing at the site of a prosthetic vascular graft years after implantation.
Clinicians should consider late malignancy at graft sites; single case leaves open any causal link to prosthetic material.
A sarcoma, arising in association with a prosthetic arterial graft, was surgically excised. The patient, a 31-year-old man, sustained a soft tissue injury to the thigh 10 years previously. A lacerated superficial femoral artery was repaired with a woven teflon-dacron graft. A large tumor surrounded, but did not invade, the graft. The tumor posed diagnostic difficulties and was thought to be either an angiosarcoma or a fibrosarcoma. Electron microscopy, performed retrospectively, showed the tumor to be probably a fibrosarcoma. The relationship of the tumor to the graft and similar experimentally induced tumors are discussed.
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Burns et al. (1972) studied this question.
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