Case report reveals fatal emphysematous hepatitis with pneumoperitoneum in an older patient, highlighting the aggressive progression of gas-forming liver infections.
Emphysematous hepatitis is a rare and fulminant gas-forming intra-abdominal infection with a high rate of mortality. Concurrent Type II Diabetes Mellitus is the most common association. It is diagnosed through CT examination with replacement of the liver parenchyma with gas without fluid-containing abscess formation. We describe the case of a gentleman in his sixties presenting with acute abdominal pain, fever and jaundice diagnosed with emphysematous hepatitis via CT with a rapidly progressive and terminal course. The imaging demonstrated large volume intrahepatic gas with pneumoperitoneum. The underlying pathogens isolated were Enterococcus faecium and Clostridium perfringens . This is believed to be the 26th case described in the literature with many similarities to previously published cases.
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Perkins et al. (2026) studied this question.
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