Key result
Primary aldosteronism represents a continuous spectrum driven by genotype-modulated adrenal biology rather than binary states.
Why the study?
Primary aldosteronism is a common, under-recognised cause of hypertension with excess cardiovascular and renal risk, requiring accurate subtype diagnosis to guide treatment.
Design
Review
Authors
Loading...
Adopts PASO criteria for standardized PA surgical outcome reporting; leaves open long-term clinical predictors in observational cohorts.
This review provides an updated framework for primary aldosteronism, linking clinical phenotypes to adrenal tissue biology and emphasizing a continuous spectrum of disease rather than a binary condition.
Wei et al. (2026) conducted a review in Primary aldosteronism. Primary aldosteronism represents a continuous spectrum from subclinical to overt disease, driven by dynamic, genotype-modulated adrenal tissue biology rather than a static binary classification.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: