What does this research mean for the field?

Anemia of prematurity is an independent risk factor for retinopathy of prematurity across all gestational ages and birth weights, with the strongest associations observed in later preterm and heavier birth weight infants. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To evaluate whether anemia of prematurity acts as an independent risk factor for retinopathy of prematurity across gestational age and birth weight categories.

August 28, 2026Retina

Anemia of Prematurity: Risk Factor for Retinopathy of Prematurity in Later Preterm and Heavier Birth Weight Neonates

View Full Paper

Ask AI

Bookmark

Authors

PMPaul Sheils MSEd SMSonia C. McNamara SASinan Akosman

Discussion

Member takes

Overview

Retrospective population-based study demonstrates anemia of prematurity increases retinopathy risk in preterm neonates, suggesting eye screening should expand to heavier, later-preterm infants.

Key Points

To evaluate whether anemia of prematurity acts as an independent risk factor for retinopathy of prematurity across gestational age and birth weight categories.
Analyzed 293,910 preterm neonates (≤36 weeks' gestational age) from the National Inpatient Sample (2016–2021).
Conducted multivariable logistic regression restricted to urban teaching hospitals, adjusting for demographics, red blood cell transfusions, oxygen exposure, respiratory distress syndrome, bronchopulmonary dysplasia, mechanical ventilation, and intraventricular hemorrhage.
Retinopathy of prematurity occurred in 2.8% of infants and was significantly more prevalent among those with anemia of prematurity compared to those without (82.4% vs. 11.7%, p < 0.001).
Anemia of prematurity was independently associated with increased odds of retinopathy across all gestational-age strata (adjusted odds ratios 2.66 to 9.63, all p < 0.01).
The strongest associations emerged in later preterm neonates (32–36 weeks) and infants with birth weights ≥1500 g.

Cite This Study

MSEd et al. (2026) studied this question.

synapsesocial.com/papers/6a91466cd15324a1df3a9fa7 https://doi.org/10.1097/iae.0000000000004999

View Full Paper

Ask AI

Bookmark

August 28, 2026Retina

Anemia of Prematurity: Risk Factor for Retinopathy of Prematurity in Later Preterm and Heavier Birth Weight Neonates

View Full Paper

Ask AI

Bookmark

Authors

PMPaul Sheils MSEd SMSonia C. McNamara SASinan Akosman

Discussion

Member takes

Overview

Retrospective population-based study demonstrates anemia of prematurity increases retinopathy risk in preterm neonates, suggesting eye screening should expand to heavier, later-preterm infants.

Key Points

To evaluate whether anemia of prematurity acts as an independent risk factor for retinopathy of prematurity across gestational age and birth weight categories.
Analyzed 293,910 preterm neonates (≤36 weeks' gestational age) from the National Inpatient Sample (2016–2021).
Conducted multivariable logistic regression restricted to urban teaching hospitals, adjusting for demographics, red blood cell transfusions, oxygen exposure, respiratory distress syndrome, bronchopulmonary dysplasia, mechanical ventilation, and intraventricular hemorrhage.
Retinopathy of prematurity occurred in 2.8% of infants and was significantly more prevalent among those with anemia of prematurity compared to those without (82.4% vs. 11.7%, p < 0.001).
Anemia of prematurity was independently associated with increased odds of retinopathy across all gestational-age strata (adjusted odds ratios 2.66 to 9.63, all p < 0.01).
The strongest associations emerged in later preterm neonates (32–36 weeks) and infants with birth weights ≥1500 g.

Cite This Study

MSEd et al. (2026) studied this question.

synapsesocial.com/papers/6a91466cd15324a1df3a9fa7 https://doi.org/10.1097/iae.0000000000004999

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

View Full Paper

Ask AI

Bookmark