Answers are grounded in this paper and cite their sources.
The guanine derivative 9-(2-hydroxyethoxymethyl) guanine (acycloguanosine), a potent inhibitor of herpes simplex virus (HSV) multiplication, was found to have marked anticellular activity against HSV-transformed thymidine kinase-positive cells. HSV type I-transformed cells were more sensitive to the drug than HSV type 2-transformed cells.
No takes yet. Share an insight, caveat, or question.
Nishiyama et al. (1979) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: