Why the study?
Chordae tension had never been measured precisely in vivo in human clinical trials, and reliable objective intraoperative data were needed to optimize length adjustment during transapical neochordae implantation.
Does a novel measuring device allow for real-time measurement of chordae tension during transapical neochordae implantation in patients undergoing mitral valve repair?
Does a novel measuring device allow for real-time measurement of chordae tension during transapical neochordae implantation in patients undergoing mitral valve repair?
A novel device enables real-time, objective measurement of chordae tension during transapical mitral valve repair, potentially shifting the paradigm from qualitative to quantitative anatomical analysis.
May enable tension-guided neochordae adjustment in mitral repair; hypothesis-generating for improved outcomes.
In this paper, we propose a very innovative designed system that enables optimal length adjustment during transapical neochordae implantation for mitral valve repair, increasing accuracy and reproducibility of neochordae length adjustment. Also, such a new device allowed real-time measurement and recording of chordae tension, producing original physiological data. To the best of our knowledge, the tension of chordae had never been measured previously as precisely, especially in in vivo human clinical trials. Preliminary experimental data have been collected on 10 selected patients, giving us the opportunity to assess for the first time the tension applied on the chordae implanted in beating human hearts. The final goal of our measuring device is to provide reliable objective intraoperative data to improve the understanding of changes occurring after mitral valve repair (MVR). This novel measuring instrument may bring change in the paradigm of MVR by allowing repair with strong objective and quantitative, instead of qualitative anatomical analysis.
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Grinberg et al. (2019) studied this question.
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