Why the study?
Sutureless aortic valve replacement is an alternative to surgical and transcatheter aortic valve replacement, prompting an evaluation of its relative effectiveness.
Does sutureless aortic valve replacement improve outcomes compared to conventional surgical or transcatheter aortic valve replacement in adults with aortic stenosis?
Population
60,689 adults with aortic stenosis across 1 randomized and 78 observational studies
Comparison
SuAVR vs SAVR and SuAVR vs TAVR
Design
Systematic review and meta-analysis
Authors
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Very-low-certainty evidence from mostly observational data precludes changing aortic valve selection; leaves open need for RCTs to guide SuAVR use.
Does sutureless aortic valve replacement improve outcomes compared to conventional surgical or transcatheter aortic valve replacement in adults with aortic stenosis?
Sutureless aortic valve replacement provides similar short- and mid-term mortality compared to SAVR and TAVR, though it is associated with higher pacemaker rates than SAVR and less paravalvular regurgitation than TAVR.
Kim et al. (2021) studied this question.
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