Why the study?
Does carotid sinus hypotension cause reflex sympathetic alpha-receptor coronary vasoconstriction independent of myocardial oxygen metabolism in dogs?
Population
Closed-chest dogs anesthetized with morphine and chloralose, with bilateral vagotomy and treated with…
Comparison
Carotid sinus hypotension and intracoronary… vs Responses after administration of the…
Design
Preclinical
Authors
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Does not support changes in human practice; leaves open translation of carotid baroreflex coronary control to clinical settings.
Does carotid sinus hypotension cause reflex sympathetic alpha-receptor coronary vasoconstriction independent of myocardial oxygen metabolism in dogs?
Carotid sinus hypotension causes reflex sympathetic alpha-receptor coronary vasoconstriction independent of changes in myocardial oxygen metabolism or aortic pressure.
Powell et al. (1979) studied this question.
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