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Apoptosis, like Helicobacter pylori, has a long history, extending back into the 19th Century. However, with the current exponential increase in the number of publications concerning H pylori, and in those written about apoptosis, it was only a matter of time before the influence of H pylori on apoptosis was investigated. We shall review the recent evidence that indicates that H pylori is capable of inducing apoptosis in gastric epithelial cells, and explore the mechanisms and major implication of this finding-that an alteration of gastric epithelial apoptosis may relate to the outcome of chronic H pylori colonisation.
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SHIRIN et al. (1998) studied this question.
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