Key result
Surgical excision followed by chemotherapy and radiotherapy resulted in no clinical evidence of recurrence at the eight-month follow-up in a 34-year-old man with extraskeletal Ewing's sarcoma of the hard palate.
Case Report (n=1)
Reports a rare case of extraskeletal Ewing's sarcoma of the hard palate successfully treated with surgery, chemotherapy, and radiotherapy.
Answers are grounded in this paper and cite their sources.
Hypothesis-generating for multimodal therapy in rare hard palate Ewing sarcoma; larger studies needed to confirm outcomes.
Extraskeletal Ewing's sarcoma (EES) is a rare soft tissue tumor morphologically indistinguishable from the more common Ewing's sarcoma of bone. We report a case of EES arising in the hard palate of 34-yr-old male patient. Microscopically, the monotonous small round cells without neuronal differentiation showed membranous positive immunoreactivity for MIC2/CD99 and vimentin. Ultrastructurally, the tumor cells showed a few intracytoplasmic organelles without evidence of neurosecretory granules or neurofilaments. The EWS-FLI1 chimeric gene was identified using the nested reverse transcriptase-polymerase chain reaction.
No takes yet. Share an insight, caveat, or question.
Kang et al. (2005) conducted a case report in Extraskeletal Ewing's Sarcoma of the hard palate (n=1). Surgical excision, multiagent chemotherapy, and radiotherapy was evaluated on Tumor recurrence. Surgical excision followed by chemotherapy and radiotherapy resulted in no clinical evidence of recurrence at the eight-month follow-up in a 34-year-old man with extraskeletal Ewing's sarcoma of the hard palate.
Synapse has enriched 10 related papers. Consider them for comparative context: