Key result
Neoadjuvant chemotherapy with vincristine, cyclophosphamide, and doxorubicin resulted in a greater than 50% reduction in tumor size in a 25-year-old female with recurrent extraskeletal Ewing's sarcoma of the breast.
Case Report (n=1)
No
This case report highlights the multimodality imaging characteristics of a rare extraskeletal Ewing's sarcoma of the breast.
May support neoadjuvant chemotherapy consideration in this rare entity; hypothesis-generating and requires prospective validation.
Extraskeletal Ewing's sarcoma (EES) is a rare soft tissue tumor that is morphologically indistinguishable from skeletal ES. We report a case of a 25-year-old female with recurrent EES/primitive neuroectodermal tumor of right breast with imaging findings on mammogram, ultrasound, magnetic resonance imaging breast, and positron emission tomography-computed tomography.
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Srivastava et al. (2016) conducted a case report in Extraskeletal Ewing's sarcoma/primitive neuroectodermal tumor of breast (n=1). Neoadjuvant chemotherapy (vincristine, cyclophosphamide, doxorubicin) and wide local excision was evaluated on Tumor size reduction. Neoadjuvant chemotherapy with vincristine, cyclophosphamide, and doxorubicin resulted in a greater than 50% reduction in tumor size in a 25-year-old female with recurrent extraskeletal Ewing's sarcoma of the breast.
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