Key result
A 35-year-old woman with hereditary thrombophilia and venous insufficiency complicated by recurrent deep vein thrombosis was successfully treated with extended anticoagulation and superficial vein surgery.
Why the study?
When chronic venous insufficiency is present and DVT occurs, it increases management complexity, especially when associated with hereditary thrombophilia.
Case Report (n=1)
No
In complex cases of recurrent DVT with hereditary thrombophilia and chronic venous insufficiency, a combination of extended anticoagulation and surgical treatment of venous insufficiency may be effective.
Thrombophilia screening in young recurrent DVT with CVI may guide duration decisions; leaves open whether it improves outcomes.
Deep Vein Thrombosis (DVT) has been associated with high morbidity and mortality risk. It could also affect the quality of life significantly. Recurrent venous thrombosis, especially in a patient of younger age, could easily be associated with hereditary thrombophilia. Additionally, there is data that thrombophilia could be associated with chronic venous disease. When chronic venous insufficiency is present and a DVT occurs, this could increase the complexity of proper management. Therefore, this report aims to describe a case of a young woman with both hereditary thrombophilia and chronic venous insufficiency of the lower extremities, complicated with recurrent DVT. The aim is also to discuss on proper management of such complex cases.
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Alexandros et al. (2025) conducted a case report in Recurrent Deep Vein Thrombosis (n=1). Anticoagulation and superficial vein surgery was evaluated on Symptom resolution and absence of thrombus recurrence. A 35-year-old woman with hereditary thrombophilia and venous insufficiency complicated by recurrent deep vein thrombosis was successfully treated with extended anticoagulation and superficial vein surgery.
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