Key result
Surgical excision followed by adjuvant chemotherapy and radiotherapy was used to treat a rare case of rectal Ewing's sarcoma in a 31-year-old female presenting with rectal bleeding.
Why the study?
Extraskeletal Ewing's sarcoma is a rare malignant soft tissue tumor with non-specific signs and symptoms, making clinical diagnosis challenging.
Case Report (n=1)
No
This case report highlights a rare presentation of extraskeletal Ewing's sarcoma in the rectum, emphasizing the necessity of histopathology and immunohistochemistry for accurate diagnosis.
Answers are grounded in this paper and cite their sources.
EES should enter the differential for bleeding rectal masses in young adults; extends known extraskeletal sites but leaves optimal management open.
Introduction: Extraskeletal Ewing’s sarcoma (EES) is a rare malignant soft tissue tumor. Those aggressive mesenchymal tumors are characterized by genetic alterations of the Ewing sarcoma gene (EWS) on chromosome 22. Signs and symptoms are usually non-specific. The clinical diagnosis of EES is challenging. Case Presentation: A 31-year-old female patient presented to our hospital with rectal bleeding. Physical examination revealed a painful and erythematous bleeding rectal mass. A pelvic MRI revealed a right-sided well-circumscribed perianal mass measuring 6.8 × 6.0 cm. Surgical excision of the rectal mass was subsequently performed. The resected specimen, including the rectal mass with a pedicle from the posterior rectal wall was sent for histopathological examination. The postoperative period was uneventful. Histopathology examination was suggestive of EES of the rectum. Clinical Discussion: EES is an unusual entity of Ewing's Sarcoma Family of Tumors, which are characterized by pathognomonic translocations. The clinical features of EES include localized pain and/or swelling. Diagnosis of EES relies on histopathology and immunohistochemistry analysis. Imaging modalities such as CT, MRI, and PET/CT are crucial to evaluate EES metastasis and assess local tumor resectability. Conclusion: Due to the rare entity of EES of the rectum, we report the case of a 31-year-old female with rectal bleeding, found to be rectal Ewing’s sarcoma.
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Saleem et al. (2023) conducted a case report in Rectal Ewing's Sarcoma (n=1). Surgical excision followed by adjuvant chemotherapy and radiotherapy was evaluated on Clinical outcome. Surgical excision followed by adjuvant chemotherapy and radiotherapy was used to treat a rare case of rectal Ewing's sarcoma in a 31-year-old female presenting with rectal bleeding.
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