Key result
Each hour of delay from admission to initiation of surgery for source control significantly decreased the odds of 60-day survival (OR 0.29) in patients with gastrointestinal perforation and septic shock.
Why the study?
Does the time from admission to initiation of surgery for source control affect 60-day survival in patients with gastrointestinal perforation and associated septic shock?
Observational (n=154)
No
Does the time from admission to initiation of surgery for source control affect 60-day survival in patients with gastrointestinal perforation and associated septic shock?
Odds Ratio: 0.29 (95% CI 0.16–0.47)
p-value: p=<0.0001
In patients with gastrointestinal perforation and septic shock, delaying surgery for source control significantly decreases 60-day survival, suggesting a target time for intervention within 6 hours of admission.
No takes yet. Share an insight, caveat, or question.
May support expedited source control; leaves open optimal timing thresholds pending prospective trials.
Azuhata et al. (2014) conducted an observational in Gastrointestinal perforation with associated septic shock (n=154). Time from admission to initiation of surgery was evaluated on 60-day survival (OR 0.29, 95% CI 0.16-0.47, p=<0.0001). Each hour of delay from admission to initiation of surgery for source control significantly decreased the odds of 60-day survival (OR 0.29) in patients with gastrointestinal perforation and septic shock.
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