The secretory cells of large axillary sweat glands from 12 normal adults were studied at the light and electron microscope levels, using techniques for localization of enzyme reaction product. The morphological and cytochemical characteristics of the plasma membrane and cell organelles (Golgi apparatus, lysosomes, mitochondria, endoplasmic reticulum, secretory granules) were observed. An interpretation of the secretory process was attempted. Most of the evidence spoke against the existence of an apocrine mechanism. Possibly some of the methods employed also could be used for the demonstration of hormone action on the LASG.
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Biempica et al. (1965) studied this question.