Key result
Contrast-enhanced CT successfully identified a rare, large tumor thrombus extending into the right atrium through the inferior vena cava in a patient with hepatocellular carcinoma.
Case Report (n=1)
Contrast-enhanced CT is useful for distinguishing bland from tumor thrombus in patients with hepatocellular carcinoma presenting with right atrial masses.
May aid contrast echo differentiation of bland versus tumor thrombus in HCC; leaves open validation in prospective series.
This is a case report of a 54-year-old patient with hepatocellular cancer under palliative chemotherapy who admitted with dyspnea on minimal exertion and peripheral oedema over the past 5 days. Echocardiogram revealed a large echogenic mass in the right atrial cavity which did not enhance with intravenous echo contrast agent, and a distended inferior vena cava (IVC) which was occluded by echogenic material with no signs of flow. To distinguish with accuracy if the thrombus was a bland or tumor thrombus, contrast-enhanced Computed Tomography (CT) was performed. CT Pulmonary Angiography and abdominal contrast-enhanced CT showed a distended and occluded IVC by a mass that extended to the right atrium and enhanced with intravenous contrast agent, and thus the mass was considered as a tumor thrombus. Due to the impaired performance status and liver function of the patient, supportive treatment was preferred instead of a surgical or radiological intervention. Large tumor thrombus extending into the right atrium through the inferior vena cava due to hepatocellular carcinoma has a rare incidence and is associated with a poor prognosis.
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Benetos et al. (2024) conducted a case report in Hepatocellular carcinoma with tumor thrombus (n=1). Contrast-enhanced Computed Tomography (CT) was evaluated. Contrast-enhanced CT successfully identified a rare, large tumor thrombus extending into the right atrium through the inferior vena cava in a patient with hepatocellular carcinoma.
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