Key result
A 71-year-old male with no prior history of liver disease presented with acute heart failure and was found to have hepatocellular carcinoma with tumor thrombus invading the right atrium.
Why the study?
Metastatic hepatocellular carcinoma typically spreads to the lungs, portal vein, and portal lymph nodes, making rare presentations like right atrial invasion important to recognize for earlier detection.
Case Report (n=1)
Hepatocellular carcinoma can rarely present as acute heart failure due to right atrial tumor invasion, even in patients without prior liver disease.
Right atrial HCC metastasis may cause acute HF without liver disease; leaves open need for broader metastatic surveillance in atypical presentations.
Metastatic hepatocellular carcinoma has been associated with a poor prognosis. Common areas of spread include the lungs, portal vein, and portal lymph nodes. Affected patients often have coexisting comorbidities, including cirrhosis, chronic hepatitis, and nonalcoholic fatty liver disease. Our case discusses a rare presentation of hepatocellular carcinoma that had spread to the right atrium, manifesting as acute heart failure in a patient with no history of liver disease. This case highlights the importance of recognizing unusual presentations of advanced hepatocellular carcinoma, as earlier detection can lead to improved patient outcomes.
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Wu et al. (2022) conducted a case report in Hepatocellular carcinoma with right atrial tumor invasion (n=1). Transatrial stent was evaluated. A 71-year-old male with no prior history of liver disease presented with acute heart failure and was found to have hepatocellular carcinoma with tumor thrombus invading the right atrium.
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