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Excerpt Myoglobinuria in man, known to be a consequence of trauma to striated muscle, has occurred also in a number of ill defined clinical circumstances. All of the latter have involved striated muscle, although without clear-cut injury. Sometimes severe muscular exercise alone has been the background; in other cases, true muscular disease, of unknown etiology, has been present. The last group consists of "Haff disease," a geographically localized, epidemic, acute affliction of muscle and idiopathic paroxysmal myoglobinuria, with or without interval muscle weakness and atrophy. The traumas to striated muscle that have resulted in myoglobinuria include crushing injuries,1arterial occlusion with...
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Berg et al. (1958) studied this question.
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