Why the study?
Does PCR improve the detection of hepatitis C virus infection compared to antibody assays in patients with chronic hepatitis after liver transplantation?
Population
25 patients with chronic hepatitis of uncertain origin after liver transplantation
Comparison
Polymerase chain reaction for detection of… vs Enzyme-linked immunoassay supplemented by…
Design
Cross-sectional
Authors
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May support PCR for HCV detection in immunosuppressed transplant recipients; hypothesis-generating and should not yet change practice.
Does PCR improve the detection of hepatitis C virus infection compared to antibody assays in patients with chronic hepatitis after liver transplantation?
PCR is more sensitive than standard antibody assays for detecting hepatitis C virus infection in immunosuppressed patients after liver transplantation.
Poterucha et al. (1992) studied this question.
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