Answers are grounded in this paper and cite their sources.
The formation and 2-amino alcohol catalyzed addition of arylzinc reagents from and with boronic acids, respectively, is drastically accelerated to a few minutes under microwave irradiation without loss of enantioselectivity (up to 98% ee). Of the amino acid derived catalysts tested, the conformationally restricted bulky substituted aziridine-2-methanols derived from serine show the best overall performance in the formation of diarylmethanols.
No takes yet. Share an insight, caveat, or question.
Braga et al. (2008) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: