Key result
In children and adolescents with type 1 diabetes, the presence of microalbuminuria was significantly associated with higher mean cholesterol (177.9 vs 142.4 mg/dl) and triglyceride levels compared to normoalbuminuria.
Cross-Sectional (n=43)
No
Absolute Event Rate: 177.9% vs 142.4%
p-value: p=<0.001
In children and adolescents with type 1 diabetes, microalbuminuria is common (20%) and associated with modifiable risk factors like blood pressure and dyslipidemia, highlighting the need for early screening.
Microalbuminuria signals higher lipids in pediatric type 1 diabetes, warranting vigilance; leaves open whether treating dyslipidemia alters nephropathy risk.
Background: The aim of this study was to determine the pattern of clinical presentation and factor associated with microalbuminuria.Methods: Urinary albumin excretion of children and adolescents diagnosed with type 1 diabetes mellitus attending diabetic clinic of Katihar medical college hospital over a period of one year. Collected blood and urine samples were analysed for glycated haemoglobin, cholesterol, triglycerides, and for 12 hour urinary albumin concentration. Blood pressures were recorded and clinical data collected.Results: During the study period 215 patients were diagnosed with type1 DM. Out of 215, fourty-three patients (20%) had persistent microalbuminuria. Factor associated with microalbuminuria in diabetic patients include duration of diabetes mellitus, higher blood pressure, higher cholesterol and triglyceride levels.Conclusion: Type 1 DM is treatable and testing is acceptable and accessible to the patients. As microalbuminuria is an early microvascular complications, it is highly recommended to screen all diabetic patients for the incidence of microalbuminuria and modifiable risk factors like dyslipidemia at the onset and then yearly assessment. Efforts need to be intensified in education of health workers and population at large for quick presentation and prompt diagnosis in order to predict overt diabetic nephropathy and also to prevent its progression.
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Amritanshu et al. (2015) conducted a cross-sectional in Type 1 diabetes mellitus (n=43). Microalbuminuria vs. Normoalbuminuria was evaluated on Mean cholesterol level (mg/dl) (p=<0.001). In children and adolescents with type 1 diabetes, the presence of microalbuminuria was significantly associated with higher mean cholesterol (177.9 vs 142.4 mg/dl) and triglyceride levels compared to normoalbuminuria.
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