What is the clinical evidence from this study?

Study design: Cohort. Population: Aneurysmal subarachnoid hemorrhage (n=305). Intervention: Pulmonary complications vs. No pulmonary complications. Primary outcome: Symptomatic vasospasm (OR 3.68, p=<0.001).

May 1, 2003Neurosurgery

Pulmonary Complications of Aneurysmal Subarachnoid Hemorrhage

Q: What are the key findings of this study?

Pulmonary complications after aneurysmal subarachnoid hemorrhage were independently associated with a higher incidence of symptomatic vasospasm (63% vs 31%; OR 3.68, P<0.001).

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Key result

Pulmonary complications after aneurysmal subarachnoid hemorrhage were independently associated with a higher incidence of symptomatic vasospasm (63% vs 31%; OR 3.68, P<0.001).

Population

305 consecutive patients with an aneurysmal subarachnoid hemorrhage source documented by angiography and…

Design

Cohort

Follow-up

mean 16 months

Authors

JFJonathan A. FriedmanMount Sinai Hospital MPMark A. PichelmannWest Virginia University DPDavid G. PiepgrasMayo Clinic

Discussion

Member takes

Implication

Pulmonary complications may flag higher vasospasm risk after aSAH; leaves open causal role and outcome impact.

Study Design

Type

Cohort (n=305)

Multicenter

Structured PICO

Population

305 consecutive patients with angiographically documented aneurysmal subarachnoid hemorrhage treated within 7 days of ictus, followed for a mean of 16 months.

Comparator

Patients without pulmonary complications

Outcome

Frequency and types of pulmonary complications and their impact on patient outcome measured by the Glasgow Outcome Scalehard clinical

Main Result

Odds Ratio: 3.68

Absolute Event Rate: 63% vs 31%

p-value: p=<0.001

Pulmonary complications after aneurysmal subarachnoid hemorrhage are common and associated with symptomatic vasospasm, but do not independently predict worse clinical outcomes when adjusted for age and admission clinical grade.

Cite This Study

Friedman et al. (2003) conducted a cohort in Aneurysmal subarachnoid hemorrhage (n=305). Pulmonary complications vs. No pulmonary complications was evaluated on Symptomatic vasospasm (OR 3.68, p=<0.001). Pulmonary complications after aneurysmal subarachnoid hemorrhage were independently associated with a higher incidence of symptomatic vasospasm (63% vs 31%; OR 3.68, P<0.001).

synapsesocial.com/papers/6a9162e431838a9342d2d3ee https://doi.org/10.1227/01.neu.0000058222.59289.f1

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May 1, 2003Neurosurgery

Pulmonary Complications of Aneurysmal Subarachnoid Hemorrhage

View Full Paper

Ask AI

Bookmark

Key result

Pulmonary complications after aneurysmal subarachnoid hemorrhage were independently associated with a higher incidence of symptomatic vasospasm (63% vs 31%; OR 3.68, P<0.001).

Population

305 consecutive patients with an aneurysmal subarachnoid hemorrhage source documented by angiography and…

Design

Cohort

Follow-up

mean 16 months

Authors

JFJonathan A. FriedmanMount Sinai Hospital MPMark A. PichelmannWest Virginia University DPDavid G. PiepgrasMayo Clinic

Discussion

Member takes

Implication

Pulmonary complications may flag higher vasospasm risk after aSAH; leaves open causal role and outcome impact.

Study Design

Type

Cohort (n=305)

Multicenter

Structured PICO

Population

305 consecutive patients with angiographically documented aneurysmal subarachnoid hemorrhage treated within 7 days of ictus, followed for a mean of 16 months.

Comparator

Patients without pulmonary complications

Outcome

Frequency and types of pulmonary complications and their impact on patient outcome measured by the Glasgow Outcome Scalehard clinical

Main Result

Odds Ratio: 3.68

Absolute Event Rate: 63% vs 31%

p-value: p=<0.001

Cite This Study

synapsesocial.com/papers/6a9162e431838a9342d2d3ee https://doi.org/10.1227/01.neu.0000058222.59289.f1

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