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We examined the sympathetic skin response in 100 normal subjects aged 20 to 91 years. The response was present in all younger subjects, but, in the elderly, was present in the lower limbs of only 50% and in the upper limbs of 73%. The amplitude of the response showed a marked decline with age in both the upper and lower limbs.
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Drory et al. (1993) studied this question.
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