Key result
Prolonged high-intensity exercise significantly increased cardiac troponin I levels (P<0.0001), and excessive increases (>370 ng/l) identified underlying subclinical coronary artery disease.
Why the study?
Does an excessive increase in cardiac troponin I following high-intensity endurance cycling detect subclinical coronary artery disease in presumably healthy leisure sport cyclists?
Population
97 recreational cyclists without known cardiovascular disease or diabetes, participating in a 91 km mountain…
Design
Cohort
Follow-up
24 hours following the race
Authors
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Excessive post-exercise troponin I rise may flag subclinical CAD in asymptomatic cyclists; observational data leaves open need for prospective validation before screening use.
Observational (n=97)
Does an excessive increase in cardiac troponin I following high-intensity endurance cycling detect subclinical coronary artery disease in presumably healthy leisure sport cyclists?
Absolute Event Rate: 69.3% vs 3.4%
p-value: p=< 0.0001
Excessively elevated cardiac troponin I levels following high-intensity exercise may serve as a marker to detect subclinical coronary artery disease in asymptomatic individuals.
Skadberg et al. (2017) conducted an observational in Subclinical coronary artery disease (n=97). Prolonged high-intensity exercise vs. Baseline (pre-race) was evaluated on Circulating cardiac troponin I levels (p=< 0.0001). Prolonged high-intensity exercise significantly increased cardiac troponin I levels (P<0.0001), and excessive increases (>370 ng/l) identified underlying subclinical coronary artery disease.
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