Key result
Emergent coronary angiography is essential for resuscitated patients without an obvious noncardiac cause, as up to 25% of those without ST elevation have a significant culprit lesion.
Why the study?
Does early coronary angiography and PCI improve outcomes in patients successfully resuscitated from out-of-hospital cardiac arrest?
Does early coronary angiography and PCI improve outcomes in patients successfully resuscitated from out-of-hospital cardiac arrest?
Emergent coronary angiography and PCI are critical post-resuscitation therapies that should be considered for all resuscitated patients without an obvious noncardiac cause, regardless of ST elevation.
Supports emergent angiography in resuscitated OHCA without obvious noncardiac cause; leaves open randomized confirmation of survival benefit.
PURPOSE OF REVIEW: The role of cardiac arrest centers, more recently termed Cardiac Receiving Centers, in improving outcomes after successful resuscitation is becoming more and more convincing. But which of all the treatments provided by Cardiac Receiving Centers are most beneficial is less certain. This review examines the role of early coronary angiography and percutaneous coronary intervention in this regard. RECENT FINDINGS: Cohort studies have consistently found that early coronary angiography is associated with improved long-term outcomes postcardiac arrest. The most common cause for out-of-hospital cardiac arrest is a myocardial ischemic event. Diagnosing and treating the underlying coronary trigger makes good physiological sense. The major issues are 'who' should undergo emergent coronary angiography and 'when' should it be done. Standard criteria such as ST segment elevation and precedent chest pains are not very sensitive in identifying those postcardiac arrest with an occluded or culprit lesion. As many as one in four postresuscitated patients without ST elevation have a significant culprit lesion, including at times an acutely occluded coronary. Cardiac Receiving Centers should have the capacity to perform emergent coronary angiography on every resuscitated patient who does not have an obvious noncardiac cause for their arrest. SUMMARY: Emergent coronary angiography and percutaneous coronary intervention are the most important Cardiac Receiving Center treatments beyond hypothermia. Providing both of these essential postresuscitation therapies is the very purpose of such centers.
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Karl B. Kern (2012) conducted a review in Out-of-hospital cardiac arrest. Emergent coronary angiography and percutaneous coronary intervention was evaluated. Emergent coronary angiography is essential for resuscitated patients without an obvious noncardiac cause, as up to 25% of those without ST elevation have a significant culprit lesion.
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