What question did this study set out to answer?

To determine the patterns of regional failure and evaluate the therapeutic reliability of selective neck dissection for metastatic squamous carcinoma of the upper aerodigestive tract.

September 1, 1999Head & Neck

Selective neck dissections for squamous carcinoma of the upper aerodigestive tract: Patterns of regional failure

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Authors

RBRobert M. ByersThe University of Texas MD Anderson Cancer Center GCGary L. ClaymanTampa General Hospital DMDiane McGillThe University of Texas MD Anderson Cancer Center

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Implication

Retrospective study reveals low regional recurrence after selective neck dissection in node-negative aerodigestive cancer, indicating postoperative radiation is essential when nodes are positive.

Key Points

To determine the patterns of regional failure and evaluate the therapeutic reliability of selective neck dissection for metastatic squamous carcinoma of the upper aerodigestive tract.
Retrospective review of medical records for patients with squamous cell carcinoma of the oral cavity, oropharynx, larynx, or hypopharynx treated from 1985 to 1990 at a single comprehensive cancer center.
Analyzed 517 selective neck dissections categorized into suprahyoid (n=41), supraomohyoid (n=284), and anterolateral (n=192) procedures.
Evaluated primary endpoints of regional neck failure and survival stratified by pathological nodal involvement and postoperative radiation therapy.
In supraomohyoid neck dissections, regional recurrence was 1.9% in pathologically node-negative necks, 35.7% in pathologically N1 disease without postoperative radiation versus 5.6% with postoperative radiation, and 14% versus 8.3% in pathologically N2B disease.
In suprahyoid neck dissections, regional recurrence reached 43% in the presence of pathologically positive lymph nodes.
Anterolateral neck dissections exhibited an overall regional failure rate of 13%; among cases with multiple pathologically positive nodes (N2B), failure was 33.3% without postoperative radiation versus 30% with radiation.

Cite This Study

Byers et al. (1999) studied this question.

synapsesocial.com/papers/6a917185252bb53f4e465a30 https://doi.org/10.1002/(sici)1097-0347(199909)21:6<499::aid-hed1>3.0.co;2-a

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Implication

Retrospective study reveals low regional recurrence after selective neck dissection in node-negative aerodigestive cancer, indicating postoperative radiation is essential when nodes are positive.

Selective neck dissections for squamous carcinoma of the upper aerodigestive tract: Patterns of regional failure

Discussion

Member takes

Implication

Key Points

Cite This Study

Selective neck dissections for squamous carcinoma of the upper aerodigestive tract: Patterns of regional failure

Discussion

Member takes

Implication

Key Points

Cite This Study

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