Key result
Three cartridges of local anesthesia with epinephrine 1:100,000 had no significant effect on systolic and diastolic blood pressure compared to anesthesia without epinephrine in hypertensive patients.
Why the study?
Does lidocaine 2% with epinephrine (1:100,000) significantly increase blood pressure in hypertensive patients undergoing tooth extraction compared to lidocaine without epinephrine?
RCT (n=88)
Lottery method
No
Does lidocaine 2% with epinephrine (1:100,000) significantly increase blood pressure in hypertensive patients undergoing tooth extraction compared to lidocaine without epinephrine?
p-value: p=0.698
The use of three cartridges of lidocaine 2% with epinephrine 1:100,000 does not significantly affect systolic or diastolic blood pressure in pre-hypertensive to stage-II hypertensive patients undergoing tooth extraction.
Does not support avoiding epinephrine in hypertensive patients; leaves open confirmation in randomized trials.
The objective of the study was to evaluate the effect of local anesthesia (Lidocaine) with epinephrine (1:100000) on blood pressure level and medicine used by hypertensive patients having Prehypertension, stage I and stage II hypertension.
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Muhammad Ilyas (2017) conducted an RCT in Hypertension (Prehypertension, Stage I, and Stage II) (n=88). Lidocaine 2% with epinephrine (1:100,000) vs. Lidocaine 2% without epinephrine (1:100,000) was evaluated on Change in systolic and diastolic blood pressure (SBP and DBP) (p=0.698). Three cartridges of local anesthesia with epinephrine 1:100,000 had no significant effect on systolic and diastolic blood pressure compared to anesthesia without epinephrine in hypertensive patients.
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