Synthesis of a triazole derivative and evaluation of their antituberculer activity

Tuberculosis (TB) is one of the major health issue which needs an immediate attention. All over the world, 18 % of people who develop TB die annually as per WHO report. A lot of research has been done since the finding of Streptomycin for treatment of this disease. Literature review suggests that 4-amino-5-(pyridin-4-yl)-4 H -1, 2, 4-triazole-3-thiol can show anti TB activity. Hence, in the present study, we have targeted to synthesize the desired compound and evaluate for its anti-TB activity.