Why the study?
Does intra-pulmonary artery infusion of fibrinolytic agents improve clot lysis compared to peripheral vein infusion in patients with massive pulmonary emboli?
Population
1 patient with massive pulmonary embolism (case report) and literature review
Comparison
Intra-pulmonary artery infusion of… vs Peripheral vein infusion of fibrinolytic agents
Design
Case_report
Authors
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Failure in this case should not alter practice; leaves open whether intra-pulmonary fibrinolysis improves lysis over peripheral infusion in massive PE.
Does intra-pulmonary artery infusion of fibrinolytic agents improve clot lysis compared to peripheral vein infusion in patients with massive pulmonary emboli?
Intra-pulmonary artery administration of fibrinolytics for massive pulmonary embolism may offer theoretical advantages in clot lysis and dosing, despite individual cases of failure.
Demeter et al. (1983) studied this question.
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