Key result
Longitudinal strain (RV-GPLS and RV-FWPLS) predicted right ventricular dysfunction following lung resection better than conventional TTE parameters (AUROCC 0.74 and 0.76, respectively; P<0.01).
Why the study?
RV dysfunction occurs following lung resection, but TTE assessment of RV function is challenging and no parameters have been validated in this population.
Do transthoracic echocardiographic measures of right ventricular systolic function accurately predict RV dysfunction compared to CMR in patients undergoing lung resection?
Observational (n=27)
Do transthoracic echocardiographic measures of right ventricular systolic function accurately predict RV dysfunction compared to CMR in patients undergoing lung resection?
Effect estimate: AUROCC 0.76 for RV-FWPLS and 0.74 for RV-GPLS
p-value: p=<0.01
Longitudinal strain (RV-GPLS and RV-FWPLS) is superior to conventional TTE parameters for assessing right ventricular systolic function following lung resection.
No takes yet. Share an insight, caveat, or question.
May aid preoperative risk stratification for lung resection; leaves open prospective validation before clinical adoption.
McCall et al. (2018) conducted an observational in Lung resection (n=27). Transthoracic echocardiographic (TTE) parameters vs. Cardiovascular magnetic resonance (CMR) was evaluated on Prediction of RV dysfunction (RVEFCMR <45%) (AUROCC 0.76 for RV-FWPLS and 0.74 for RV-GPLS, p=<0.01). Longitudinal strain (RV-GPLS and RV-FWPLS) predicted right ventricular dysfunction following lung resection better than conventional TTE parameters (AUROCC 0.74 and 0.76, respectively; P<0.01).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: