Key result
Impaired right ventricular global longitudinal strain (≥ -15.4%) was significantly associated with an increased risk of adverse clinical outcomes (HR 5.46) in patients with ischemic cardiomyopathy.
Why the study?
Do right ventricular global longitudinal strain and strain rate correlate with CMR RVEF and predict adverse clinical outcomes in patients with ischemic cardiomyopathy?
Population
57 patients with ischemic cardiomyopathy, mean age 64, 75% male, US-based. Excluded: age > 80 years, severe…
Comparison
Measurement of right ventricular global… vs Cardiac magnetic resonance right ventricular…
Design
Cohort, Investigator analyzing strain images was blinded to the conventional…
Follow-up
15 ± 9 months
Authors
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RV strain may refine risk stratification in ischemic cardiomyopathy; hypothesis-generating and should not yet change practice.
Observational (n=57)
No
Do right ventricular global longitudinal strain and strain rate correlate with CMR RVEF and predict adverse clinical outcomes in patients with ischemic cardiomyopathy?
Hazard Ratio: 5.46 (95% CI 1.18–25.2)
p-value: p=0.030
RV global longitudinal strain and strain rate correlate strongly with CMR-derived RV ejection fraction and serve as independent predictors of adverse clinical outcomes in patients with ischemic cardiomyopathy.
Park et al. (2014) conducted an observational in Ischemic cardiomyopathy (n=57). Impaired right ventricular global longitudinal strain (RVGLS ≥ -15.4%) vs. Preserved RVGLS (< -15.4%) was evaluated on Composite of death, hospital admission for heart failure, and heart transplantation (HR 5.46, 95% CI 1.18-25.20, p=0.030). Impaired right ventricular global longitudinal strain (≥ -15.4%) was significantly associated with an increased risk of adverse clinical outcomes (HR 5.46) in patients with ischemic cardiomyopathy.
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