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December 15, 2004Cancer ResearchOpen Access

Intratumor Heterogeneity of Cancer/Testis Antigens Expression in Human Cutaneous Melanoma Is Methylation-Regulated and Functionally Reverted by 5-Aza-2′-deoxycytidine

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Authors

LSLuca SigalottiCentro di Riferimento OncologicoEFElisabetta FrattaCentro di Riferimento OncologicoSCSandra CoralUniversity of Siena

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Sigalotti et al. (2004) studied this question.

synapsesocial.com/papers/6a917a4790ff22de3cb3ade1https://doi.org/10.1158/0008-5472.can-04-1442
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Also Consider

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  1. 1A new family of genes coding for an antigen recognized by autologous cytolytic T lymphocytes on a human melanoma.1995 · 576 citations
  2. 2Simultaneous Humoral and Cellular Immune Response against Cancer–Testis Antigen NY-ESO-1: Definition of Human Histocompatibility Leukocyte Antigen (HLA)-A2–binding Peptide Epitopes1998 · 731 citations
  3. 3Prolonged Upregulation of the Expression of HLA Class I Antigens and Co stimulatory Molecules on Melanoma Cells Treated with 5-aza-2??-deoxycytidine (5-AZA-CdR)1999 · 129 citations
  4. 4Immunoselection in vivo: Independent loss of MHC class I and melanocyte differentiation antigen expression in metastatic melanoma1997 · 305 citations
  5. 5Demethylation of a hypermethylated P15/INK4B gene in patients with myelodysplastic syndrome by 5-Aza-2′-deoxycytidine (decitabine) treatment2002 · 522 citations