Comparative therapeutic efficacy of intramammary Ceftiofur hydrochloride and Cefalonium during dry period in buffaloes

This is the authors' abstract. We don't add key points for this paper.

Subclinical Mastitis (SCM) is mainly the major form of mastitis in modern livestock dairy animals. Antibiotic dry animal therapy proves to decrease risk of early lactation SCM. This study was designed to differentiate and compare efficacy of intramammary preparations i.e., Ceftiofur hydrochloride and Cefalonium during the dry period in buffaloes. The proposed work was carried out at ICAR- CIRB, Hisar, Haryana. Seventy-five buffaloes positive for SCM were randomized in three groups with 25 buffaloes in each group- two treatment groups (T2 and T3) and one untreated control group (T1). T2 group buffaloes were treated with drug Ceftiofur hydrochloride (500 mg) and T3 group with Cefalonium formulation (250 mg). Therapeutic efficacies of both the drugs were evaluated based on bacterial cure rates and Odd Ratios (OR). T2 treatment group showed better therapeutic response as compared to T3 groups the bacterial cure rate was 88% and 48% respectively, and the Odd Ratio (OR) of treatment group T2 was 0.0057 which was lower as compared to group T3 which was 0.0451.