This case report highlights a potential familial or genetic predisposition to rheumatic heart disease and mitral stenosis among identical twins.
May suggest familial predisposition to rheumatic mitral stenosis; leaves open confirmation of genetic factors in larger studies.
THE increased incidence of rheumatic fever and A rheumatic heart disease in certain families has been commented on extensively in the literature.1 2 3 4 5 The purpose of this paper is to report the findings of mitral stenosis in a set of identical twins whose twin sisters had previously died of complications of rheumatic heart disease.Case ReportsCase 1. C.B.K. (A-2552), a 36-year-old man, entered the Salt Lake Veterans Administration Hospital for evaluation of rheumatic heart disease. He had been discharged from the Army 17 years previously because of a "heart condition" manifested at that time by dyspnea on exertion and hemoptysis. . . .
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Frederic C. Chang (1961) studied this question.
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