Why the study?
Does surgical repair of atrial septal defects significantly change ventricular dimensions and interventricular septal motion in the early postoperative period?
Does surgical repair of atrial septal defects significantly change ventricular dimensions and interventricular septal motion in the early postoperative period?
Surgical repair of atrial septal defects leads to significant and rapid improvements in right and left ventricular dimensions and interventricular septal motion within 3 to 8 days postoperatively.
Rapid ventricular remodeling occurs early after ASD repair; supports prior reports but leaves open long-term impact in cohort data.
Fifteen consecutive adult patients with uncomplicated atrial septal defects (ASD) underwent echocardiographic examinations both before and 3-8 days (mean 7 days) after surgery to study the early postoperative changes in cardiac dimensions and interventricular septal motion. Echocardiographic analyses included patterns of interventricular septal motion, right and left ventricular dimensions at end-diastole (RVDd & LVDd), aortic root dimension at end-diastole (ARDd) and left atrial dimension at end-systole (LADs). The results showed that the septal motion was abnormal in 87% (13/15) before and 40% (6/15) after operation. RVDd decreased from 36 +/- 7 mm to 27 +/- 7 mm (p less than 0.01) while LVDd increased from 33 +/- 6 mm to 39 +/- 4 mm (p less than 0.01). There were no significant changes in LADs and ARDd after surgery. These observations suggest that in patients with ASD the ventricular dimensions and patterns of interventricular septal motion are changed significantly shortly after surgical repair.
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Chang et al. (1985) studied this question.
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