Key result
Preoperative B-mode ultrasonography predicted plaque hemorrhage, with all 5 hypoechoic plaques showing hemorrhage compared to none of the 13 hyperechoic plaques.
Why the study?
Can preoperative ultrasonography predict plaque hemorrhage and clinical symptoms in patients undergoing carotid endarterectomy?
Observational (n=22)
Yes
Can preoperative ultrasonography predict plaque hemorrhage and clinical symptoms in patients undergoing carotid endarterectomy?
Preoperative B-mode ultrasonography can predict plaque hemorrhage based on hypoechogenicity, and turbulent flow may be associated with clinical symptoms in carotid artery stenosis.
May support preoperative identification of hemorrhage-prone plaques in CEA; leaves open validation for symptom prediction or practice change.
Ultrasonography was applied to 24 carotid arteries in 22 patients prior to carotid endarterectomy (CEA) . The relationships between the histology of the plaque removed by CEA, especially the presence or absence of plaque hemorrhage (PH) and the echogenicity in B-mode imaging, and between clinical symptoms and turbulent flow (TF) around the plaque revealed by color flow imaging, were examined. The echogenicity of the plaque was divided into 3 grade based on comparison with that of the intimal layer: Low, in which echogenicity was hypoechoic relative to the intimal layer (5 plaques), Iso, in which echogenicity was the same as that of the intimal layer (6 plaques), High, in which echogenicity was hyperechoic relative to the intimal layer (13 plaques) . PH was found in 7 of the 24 plaques. All 5 of the hypoechoic plaques showed PH, whereas none of the 13 hyperechoic plaques didso. TF was detected in 11 of the 24 carotid arteries. Clinical symptoms occurred in 7 of the 11 patients with TF and 3 of those without TF. In conclusion, we have shown that this technique is capable of predicting the occurrence of PH due to its echogenicity in B-mode imaging. We also suggest that TF may play a role in the production of clinical symptoms.
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Nishitani et al. (1996) conducted an observational in Extracranial carotid artery stenosis (n=22). Preoperative ultrasonography (B-mode and color flow imaging) vs. Histological findings of removed plaque was evaluated on Presence of plaque hemorrhage based on echogenicity. Preoperative B-mode ultrasonography predicted plaque hemorrhage, with all 5 hypoechoic plaques showing hemorrhage compared to none of the 13 hyperechoic plaques.
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