Key result
Higher fasting blood glucose was independently associated with microvascular obstruction in 108 nondiabetic STEMI patients undergoing primary percutaneous coronary intervention.
Why the study?
The relationship between fasting blood glucose and microvascular obstruction after primary PCI remains unclear in nondiabetic patients with STEMI.
Does fasting blood glucose predict microvascular obstruction in nondiabetic STEMI patients after primary PCI?
Observational (n=108)
Does fasting blood glucose predict microvascular obstruction in nondiabetic STEMI patients after primary PCI?
Fasting blood glucose is an independent predictor of microvascular obstruction in nondiabetic patients presenting with STEMI and undergoing primary PCI.
May aid MVO risk stratification after primary PCI in nondiabetic STEMI; leaves open need for validation before clinical use.
BACKGROUND: The relationship between fasting blood glucose (FBG) and microvascular obstruction (MVO) after primary percutaneous coronary intervention (PCI) remains unclear in nondiabetic patients with ST-segment elevation myocardial infarction (STEMI). This study aimed to determine the predictive value of FBG in MVO in nondiabetic STEMI patients. METHODS: A total of 108 nondiabetic STEMI patients undergoing primary PCI were enrolled in this study. The patients were classified into either the MVO group or non-MVO group based on cardiac magnetic resonance imaging (CMR). RESULTS: FBG in the MVO group was higher than in the non-MVO group. Univariate analysis showed that FBG, peak high-sensitive troponin T (TnT), pre-PCI thrombolysis in myocardial infarction (pre-PCI TIMI) flow, left ventricular ejection fraction (LVEF), infarction size, left ventricular end-diastolic diameter (LVEDd), left ventricular end-diastolic volume (LVEDV), and global longitudinal strain (GLS) were likely predictive factors of MVO. After adjustment for other parameters, FBG, peak TnT, LVEF, and LVEDV remained independent predictors for MVO. CONCLUSION: FBG was independently associated with MVO in nondiabetic STEMI patients.
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Wu et al. (2020) conducted an observational in ST-segment elevation myocardial infarction (STEMI) (n=108). Fasting blood glucose was evaluated on Microvascular obstruction (MVO). Higher fasting blood glucose was independently associated with microvascular obstruction in 108 nondiabetic STEMI patients undergoing primary percutaneous coronary intervention.
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