Population
BDF1 mice with P388 or L-1210 leukemia, C3H mice with Gross leukemia, and HeLa cells in vitro.
Comparison
New anthracycline glycosides obtained by nitrous… vs Daunorubicin and doxorubicin.
Design
Preclinical
Follow-up
up to 60 days (for long-term survivors)
Authors
Loading...
Hypothesis-generating for novel anthracyclines in leukemia models; clinical translation remains open.
New anthracycline glycosides obtained by nitrous acid deamination show promising antileukemic activity in mice, including oral efficacy for compound 13.
Cassinelli et al. (1985) studied this question.
Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context: