Key result
Lisinopril (44.28%) and biguanides (63.1%) were the most commonly prescribed antihypertensive and antidiabetic medications, with dual therapy being the most frequent prescribing pattern.
Why the study?
Prescribing pattern surveys provide drug use evaluation to capture an unbiased picture and identify suboptimal prescribing patterns of antihypertensive and antidiabetic pharmacotherapies.
Cross-Sectional (n=360)
Yes
The study highlights that dual therapy is the most common prescribing pattern for hypertension and diabetes in North Central Nigeria, with a high reliance on branded medications over generics.
Answers are grounded in this paper and cite their sources.
Prescribing audits may guide local optimization in Nigeria; leaves open effects on control and outcomes.
Background: Antihypertensive and antidiabetic pharmacotherapy effectively reduces hypertension and diabetic-related morbidity and mortality. Prescribing pattern surveys is one of the drug use evaluation techniques providing an unbiased picture and identification of suboptimal prescribing patterns. The aim of the study is to describe prescription pattern of antihypertensives and antidiabetics in public and private healthcare centres. Method: A cross sectional retrospective study was conducted to obtain related information from prescriptions of 360 patients treated for hypertension and diabetic-related ailments at the public and missionary hospitals, private clinics and community pharmacies with the aid of a data collection sheet. Results: One hundred sixty eight (47.6%) of the patients whose prescription were evaluated were male, with 192 (53.3%) been female counterparts. Those from 45 years and above constituted the highest percentage (76.6%) that were managed for hypertension and diabetic-related ailments across the facilities. Most of the patients (84.2%) were married people, and many of them (45.8%) were government workers. Lisinopril was the highest prescribed in the facilities (44.28%) compared to other antihypertensives, followed by amlodipine ((38.42%), with hydralazine been the least prescribed (0.4%). For the antidiabetics, biguanides were the most commonly prescribed medicine (63.1%), compared to the sulphonyl urea (27.55%. With respect to number of antidiabetics per prescription, two drugs were the most prescribed pattern (86.3%), and dual therapy were the most prescribed in the faith based (83.20%), private (96.40%) and public (94.4%) healthcare facilities. In all, majority (68.5%) of the prescriptions were by brand with 31.5% by generics names. Conclusion: Diuretics were the most prescribed antihypertensive across faith based, government owned and private health care centres and most patient required two drugs to maintain their blood pressure mostly combined. Biguanides were the most prescribed class of antidiabetics. For hypertension comorbid with diabetes, Biguanides, Sulphonylureas, Glyptins and insulin were mostly combined. Branded medications were more prescribed than generics.
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Dangiwa et al. (2022) conducted a cross-sectional in Hypertension and diabetes (n=360). Antihypertensives and antidiabetics was evaluated on Prescribing patterns of antihypertensives and antidiabetics. Lisinopril (44.28%) and biguanides (63.1%) were the most commonly prescribed antihypertensive and antidiabetic medications, with dual therapy being the most frequent prescribing pattern.
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